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Updated: May 11, 2026

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa
13:40

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa

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Las vías de absorción de fármacos del transportador multidrogas AcrB estudiadas mediante simulaciones moleculares y

Xin-Qiu Yao1, Nobuhiro Kimura, Satoshi Murakami

  • 1Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

Journal of the American Chemical Society
|May 1, 2013
PubMed
Resumen

La resistencia a múltiples fármacos en Escherichia coli involucra la bomba de eflujo AcrB. Las vías de absorción de fármacos a través de AcrB dependen de las propiedades del fármaco, con vías distintas para moléculas hidrofóbicas, lipofílicas, más pequeñas y más grandes.

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