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La formación de anillos espiro es catalizada por una dioxigenasa multifuncional en la biosíntesis del austinol

Yudai Matsuda1, Takayoshi Awakawa, Toshiyuki Wakimoto

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|July 20, 2013
PubMed
Resumen

Los investigadores esclarecieron la biosíntesis fúngica del austinol, un meroterpenoide. Las enzimas clave, incluida una dioxigenasa multifuncional (AusE), catalizan la formación estereospecífica de su único sistema de anillos de espiro-lactona.

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