Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Recurrence or persistence of atrial fibrillation is associated with frailty and adverse outcomes: the SAGE-AF cohort study.

BMC geriatrics·2026
Same author

The prevalence and burden of chronic kidney disease, patterns of anticoagulation prescribing, and major bleeding risk in older adults with atrial fibrillation.

BMC geriatrics·2025
Same author

Need for Engagement in Stroke Prevention Shared Decision-Making in Older Adults with Atrial Fibrillation and Multimorbidity.

Advances in geriatric medicine and research·2025
Same author

Fazekas score predicts cognitive decline & frailty in older adults: insights from the SAGE-AF cohort study.

Neurological research and practice·2025
Same author

Multiclass Arrhythmia Classification Using Multimodal Smartwatch Photoplethysmography Signals Collected in Real-Life Settings.

IEEE transactions on bio-medical engineering·2025
Same author

Multiclass arrhythmia classification using multimodal smartwatch photoplethysmography signals collected in real-life settings.

Research square·2024

Video Experimental Relacionado

Updated: May 8, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Delirio en personas mayores.

Sharon K Inouye1, Rudi G J Westendorp2, Jane S Saczynski3

  • 1Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.

Lancet (London, England)
|September 3, 2013
PubMed
Resumen

El delirio, un trastorno cognitivo agudo común y grave en adultos mayores, requiere un diagnóstico formal. La prevención no farmacológica es la más efectiva, ya que los tratamientos farmacológicos carecen de evidencia.

Más Videos Relacionados

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Videos de Experimentos Relacionados

Last Updated: May 8, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Área de la Ciencia:

  • Geriatría La geriatría es la especialidad de la geriatría.
  • Neurología Neurología.
  • Salud Pública La salud pública.

Sus antecedentes:

  • El delirio es un trastorno agudo frecuente, grave y a menudo fatal que afecta la atención y la cognición en personas de 65 años o más.
  • Es poco reconocido a pesar de los costos significativos y la mortalidad.
  • El diagnóstico se basa en la evaluación cognitiva formal y una historia de aparición de síntomas agudos.

Objetivo del estudio:

  • Revisar la comprensión actual del delirio en los ancianos.
  • Para resaltar estrategias efectivas de prevención y tratamiento.
  • Para enfatizar el papel del delirio en la comprensión de la fisiopatología del cerebro y la seguridad del paciente.

Principales métodos:

  • Revisión de la literatura existente sobre el diagnóstico, la prevención y el tratamiento del delirio.
  • Análisis de las implicaciones del delirio para la salud cerebral y la seguridad del paciente.
  • Discusión de las prioridades de salud pública relacionadas con el delirio.

Principales resultados:

  • Los enfoques multicomponentes y no farmacológicos son la estrategia más efectiva para la prevención del delirio.
  • No hay evidencia convincente que respalde la eficacia de la prevención o el tratamiento farmacológico.
  • Se recomienda la reducción de fármacos para sedación y analgesia, junto con métodos no farmacológicos.

Conclusiones:

  • El delirio sirve como un marcador de vulnerabilidad cerebral y un mecanismo potencial para el daño cognitivo.
  • Abordar el delirio es crucial para mejorar la seguridad del paciente e impulsar mejoras en los procesos de todo el sistema.
  • Los esfuerzos de salud pública deben centrarse en la mejora de la codificación, el reembolso, la financiación de la investigación y la educación para los médicos y el público.