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Updated: May 8, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

Rh2(R-TPCP)4-catalizado por la enantioselectiva [3+2]-cicloadición entre nitrones y vinildiazoacetatos

Changming Qin1, Huw M L Davies

  • 1Department of Chemistry, Emory University , 1515 Dickey Drive, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|September 13, 2013
PubMed
Resumen

Este estudio introduce una reacción catalizada por rodio entre vinildiazoacetatos y nitrones, produciendo eficientemente 2,5-dihidroisoxazoles quirales a través de la cicloadición asimétrica. Los catalizadores de dirhodium demostraron ser óptimos para este versátil método sintético.

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