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Updated: May 7, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Published on: February 7, 2019

Diseño, preparación e implementación de un biaril P,N-ligando quiral basado en imidazol para la catálisis asimétrica

Flavio S P Cardoso1, Khalil A Abboud, Aaron Aponick

  • 1Department of Chemistry, University of Florida , P.O. Box 117200, Gainesville, Florida 32611, United States.

Journal of the American Chemical Society
|September 19, 2013
PubMed
Resumen

Los investigadores desarrollaron una nueva estrategia para crear compuestos biarílicos quirales con heterociclos de 5 miembros. Se sintetizó un ligando basado en imidazol y demostró ser altamente efectivo en las reacciones de acoplamiento A(3) enantioselectivas.

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