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Kir3.x específico del atrio determina la inducibilidad, la dinámica y la terminación de la fibrilación mediante la

Brian O Bingen1, Zeinab Neshati, Saïd F A Askar

  • 1Laboratory of Experimental Cardiology, Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands (B.O.B., Z.N., S.F.A.A., D.L.Y., M.J.S., A.A.V.d.V., D.A.P.); and Department of Physics and Astronomy, Ghent University, Ghent, Belgium (I.V.K., A.V.P.).

Circulation
|September 26, 2013
PubMed
Resumen

El bloqueo de los canales Kir3.x específicos de la aurícula termina efectivamente la fibrilación auricular al prolongar la duración del potencial de acción. Este estudio identifica a Kir3.x como un objetivo prometedor para nuevos fármacos antiarrítmicos.

Palabras clave:
Los canales de potasio de rectificación hacia adentro acoplados a la proteína G rectifican los canales de potasio.La interferencia del ARN en el ARN.potenciales de acción potenciales de acciónLa arritmia es una arritmia.La fibrilación auricular es una fibrilación auricular.El cardiomiocito es un cardiomiocito.Imágenes de colorantes sensibles a la tensión para la obtención de imágenes.

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