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Updated: May 6, 2026

Generation and Isolation of Cell Cycle-arrested Cells with Complex Karyotypes
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La haploinsuficiencia y la triplosensibilidad acumuladas impulsan patrones de aneuploidía y dan forma al genoma del

Teresa Davoli1, Andrew Wei Xu, Kristen E Mengwasser

  • 1Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Division of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.

Cell
|November 5, 2013
PubMed
Resumen

Un nuevo método computacional, TUSON Explorer, identifica los genes impulsores del cáncer y explica los patrones recurrentes de aneuploidía. Revela un continuo de potencial oncogénico, lo que sugiere que la haploinsufficiencia y la triplosensibilidad acumuladas dan forma a los genomas del cáncer.

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