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La diferenciación celular TH17 está regulada por el reloj circadiano

Xiaofei Yu1, Darcy Rollins, Kelly A Ruhn

  • 1Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|November 9, 2013
PubMed
Resumen

El reloj circadiano controla directamente el desarrollo de las células T auxiliares 17 (T ((H) 17), cruciales para la inmunidad. Esta regulación, mediada por NFIL3 y REV-ERBα, tiene un impacto en la susceptibilidad a las enfermedades inflamatorias.

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