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Efectos antidiabéticos de los disruptores de pequeñas moléculas de la proteína reguladora de la glucokinasa

David J Lloyd1, David J St Jean2, Robert J M Kurzeja2

  • 1Department of Metabolic Disorders, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, USA.

Nature
|November 15, 2013
PubMed
Resumen

Los investigadores identificaron nuevos compuestos que interrumpen la interacción entre la proteína reguladora de la glucokinasa y la glucokinasa, normalizando la glucosa en sangre en roedores diabéticos. Este enfoque muestra potencial para el tratamiento de la diabetes tipo II con un riesgo reducido de hipoglucemia.

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