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Updated: Jul 6, 2026

Using the E1A Minigene Tool to Study mRNA Splicing Changes
10:25

Using the E1A Minigene Tool to Study mRNA Splicing Changes

Published on: April 22, 2021

Un papel para las secuencias de exones y la proximidad del sitio de empalme en la selección del sitio de empalme

R Reed, T Maniatis

    Cell
    |August 29, 1986
    PubMed
    Resumen

    Las secuencias de exones y la proximidad del sitio de empalme influyen significativamente en la selección del sitio de empalme del ARN en la beta-globina humana. La alteración de las secuencias de exones o la dilución de los factores de empalme afectan a los sitios de empalme utilizados, lo que indica factores limitantes en el proceso.

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