Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Archival Research01:40

Archival Research

15.6K
Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
15.6K
Ethics in Research01:56

Ethics in Research

23.7K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.7K
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

596
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
596
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

627
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
627
Improving Translational Accuracy02:07

Improving Translational Accuracy

11.6K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
11.6K
Improving Translational Accuracy02:07

Improving Translational Accuracy

2.6K
2.6K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Development and acceptability of gist-based decision aids for prostate and breast cancer screening: a two-phase qualitative interview study in an online setting.

BMJ open·2026
Same author

Measurement of ethnicity in clinical trials: Delphi survey and consensus statement.

BMJ (Clinical research ed.)·2026
Same author

Patient Engagement With an Electronic Patient-Reported Outcomes Tool Evaluating Hospital Discharge Readiness After Cancer Surgery.

JCO oncology practice·2026
Same author

Nerve Blocks for Mastectomy with Reconstruction: Reply.

Anesthesiology·2026
Same author

Protocol for a SPIRIT extension for reporting pragmatic and explanatory trial protocols designed using the PRECIS tool (SPIRIT-PRECIS).

Journal of clinical epidemiology·2026
Same author

SPIRIT 2025 statement: updated guideline for protocols of randomised trials.

Lancet (London, England)·2026

Video Experimental Relacionado

Updated: May 4, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

14.4K

Aumentar el valor y reducir el desperdicio: abordar la investigación inaccesible.

An-Wen Chan1, Fujian Song2, Andrew Vickers3

  • 1Women's College Research Institute, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Lancet (London, England)
|January 14, 2014
PubMed
Resumen

La difusión de la investigación en salud es pobre, con acceso limitado a protocolos, informes y datos. Esto lleva a inversiones desperdiciadas y resultados sesgados, perjudicando la atención al paciente y el progreso de la investigación.

Más Videos Relacionados

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.9K
Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research
13:25

Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research

Published on: April 22, 2022

4.1K

Videos de Experimentos Relacionados

Last Updated: May 4, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

14.4K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.9K
Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research
13:25

Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research

Published on: April 22, 2022

4.1K

Área de la Ciencia:

  • Investigación de la salud Investigación de la salud.
  • Investigación biomédica en la investigación biomédica.
  • Los ensayos clínicos son ensayos clínicos.

Sus antecedentes:

  • La documentación de la investigación en salud incluye protocolos, informes completos y conjuntos de datos.
  • Estos documentos esenciales rara vez están disponibles, lo que lleva a una información incompleta.
  • Los informes de revistas a menudo se informan de manera selectiva e incompleta, lo que dificulta la reproducibilidad de la investigación.

Objetivo del estudio:

  • Para resaltar el problema crítico de los datos de investigación de salud inaccesibles.
  • Para subrayar las consecuencias negativas de la mala difusión de datos.
  • Proponer soluciones sistémicas para mejorar la transparencia de la investigación y el intercambio de datos.

Principales métodos:

  • El estudio es una revisión y análisis de las prácticas actuales en la documentación y difusión de la investigación en salud.
  • Examina la disponibilidad y la calidad de los protocolos de estudio, los informes completos del estudio y los conjuntos de datos a nivel de participantes.
  • Identifica las barreras sistémicas y propone recomendaciones accionables.

Principales resultados:

  • Los protocolos, los informes completos de los estudios y los conjuntos de datos a nivel de participantes rara vez son accesibles.
  • Los informes de revistas disponibles sufren de informes selectivos y omisiones metodológicas.
  • El acceso incompleto a los datos da como resultado miles de millones de dólares en inversiones desperdiciadas e introduce sesgo.

Conclusiones:

  • Las instituciones académicas y los financiadores deben incentivar la plena difusión de la investigación.
  • Es crucial desarrollar y adoptar estándares rigurosos para protocolos, informes y intercambio de datos.
  • Las revistas, los financiadores y los reguladores deben hacer cumplir las políticas para el registro de estudios y la disponibilidad de datos.