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Riesgo de infarto de miocardio y accidente cerebrovascular después de bacteriemia adquirida en la comunidad: un
Michael Dalager-Pedersen1, Mette Søgaard, Henrik Carl Schønheyder
1Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark (M.D.-P., H.N.); Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark (M.D.-P., M.S., R.W.T.); and Department of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark (H.C.S.).
Circulation
|February 14, 2014
Resumen
La bacteriemia adquirida en la comunidad aumenta significativamente el riesgo a corto plazo de infarto de miocardio y accidente cerebrovascular. Este aumento en el riesgo de eventos cardiovasculares es más pronunciado dentro de los 30 días posteriores a la infección.
Área de la Ciencia:
- Cardiología Cardiología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Epidemiología La epidemiología.
Sus antecedentes:
- Las infecciones pueden precipitar eventos cardiovasculares agudos.
- El riesgo específico de infarto de miocardio y accidente cerebrovascular después de la bacteriemia adquirida en la comunidad sigue siendo en gran medida desconocido.
Objetivo del estudio:
- Para evaluar el riesgo de infarto agudo de miocardio y accidente cerebrovascular isquémico dentro de un año después de la bacteriemia adquirida en la comunidad.
Principales métodos:
- Estudio de cohorte basado en la población en el norte de Dinamarca que involucró a 4389 pacientes hospitalizados con bacteremia.
- Comparación de pacientes con bacteriemia con la población general y controles hospitalizados no bacteriémicos.
- Determinación de eventos de infarto de miocardio y accidente cerebrovascular a través de bases de datos de atención médica durante 365 días.
- Análisis de regresión multivariable para determinar los riesgos relativos y las proporciones de peligro.
Principales resultados:
- Se observó un aumento sustancial del riesgo de infarto de miocardio o accidente cerebrovascular dentro de los 30 días posteriores a la bacteriemia (riesgo relativo ajustado de 20,86 frente a los controles de la población).
- Un aumento modesto en el riesgo persistió de 31 a 180 días en comparación con los controles de la población (proporción de riesgo ajustada 1.64).
- No se observaron diferencias significativas en el riesgo cardiovascular después de seis meses, independientemente del grupo de control.
Conclusiones:
- La bacteriemia adquirida en la comunidad está relacionada con un mayor riesgo a corto plazo de infarto de miocardio y accidente cerebrovascular.
- Los hallazgos destacan la importancia de monitorear la salud cardiovascular en pacientes después de la bacteremia.
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