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La medicina individualizada desde el pre-útero hasta la tumba
1The Scripps Translational Science Institute, The Scripps Research Institute and Scripps Health, La Jolla, CA 92037, USA.
Cell
|April 1, 2014
Resumen
Cada individuo es biológicamente único, incluso los gemelos idénticos. Comprensivo y completo.
Área de la Ciencia:
- La genómica y la medicina personalizada
Sus antecedentes:
- La singularidad biológica a menudo se subestima, incluso en gemelos idénticos.
- Los avances en las tecnologías ómicas permiten un perfil biológico individual detallado.
Objetivo del estudio:
- Para resaltar la profunda singularidad biológica de cada individuo.
- Para enfatizar el potencial de los datos omics integrales en el cuidado de la salud.
Principales métodos:
- Evaluación integral de los ómicos, incluida la secuenciación de ADN / ARN.
- Caracterización del proteoma, el metaboloma, el microbioma, los autoanticuerpos y el epigenoma.
Principales resultados:
- Demostró que cada persona posee un contenido biológico único en su tipo.
- Se confirmó una variación individual significativa más allá de los marcadores tradicionales como las huellas dactilares.
Conclusiones:
- Los datos biológicos individualizados ofrecen oportunidades sin precedentes para el tratamiento médico.
- Los datos personalizados pueden impulsar el desarrollo de nuevas estrategias de salud preventiva.
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