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Un mecanismo de "empujar y deslizar" permite la translocación insensible a la secuencia de proteínas secretoras por

Benedikt W Bauer1, Tom Shemesh1, Yu Chen1

  • 1Howard Hughes Medical Institute, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.

Cell
|June 7, 2014
PubMed
Resumen

Las bacterias utilizan la SecA ATPasa y el canal SecY para la translocación de proteínas. Un mecanismo de "empujar y deslizar" explica cómo SecA mueve diversos polipéptidos a través del canal SecY, involucrando la unión de ATP y la hidrólisis.

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