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Videos de Conceptos Relacionados

Microbiota of the Large Intestine01:27

Microbiota of the Large Intestine

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The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
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Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

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The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...
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Microbiota of the Stomach and Small Intestine01:27

Microbiota of the Stomach and Small Intestine

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The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
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Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

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Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity,...
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Immune Surveillance by NK Cells and Phagocytes01:25

Immune Surveillance by NK Cells and Phagocytes

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Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
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NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
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Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

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The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
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Video Experimental Relacionado

Updated: Apr 26, 2026

Time-lapse Imaging of Mouse Macrophage Chemotaxis
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Movilidad GI: la microbiota y los macrófagos unen sus fuerzas.

Michelle L Robinette1, Marco Colonna1

  • 1Washington University School of Medicine, St. Louis, MO 63110, USA.

Cell
|July 19, 2014
PubMed
Resumen

El intestino del estómago.

Área de la Ciencia:

  • Gastroenterología y Gastroenterología.
  • Neuroinmunología La neuroinmunología.
  • Microbiología Microbiología.

Sus antecedentes:

  • La motilidad gastrointestinal es crucial para la digestión, regulada por el sistema nervioso entérico.
  • Las funciones complejas del intestino implican contracciones del músculo liso y control neuronal.

Objetivo del estudio:

  • Para investigar los mecanismos reguladores de la motilidad gastrointestinal.
  • Explorar la interacción entre el sistema nervioso entérico, el sistema inmunológico y la microbiota intestinal.

Principales métodos:

  • El estudio incluyó el análisis de las interacciones entre el sistema nervioso entérico, el sistema inmunológico y la microbiota intestinal.
  • La investigación se centró en la regulación fisiológica de las funciones intestinales.

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Videos de Experimentos Relacionados

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Principales resultados:

  • Muller y otros. Descubrieron que el sistema inmunológico y la microbiota intestinal influyen significativamente en la motilidad gastrointestinal.
  • Esta interacción agrega una nueva capa reguladora a los procesos digestivos.

Conclusiones:

  • La red reguladora del intestino para la motilidad es más compleja de lo que se entendía anteriormente.
  • La integración de factores inmunológicos y microbianos es clave para comprender la salud digestiva.