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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
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A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
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El tracoma es un tracoma.

Hugh R Taylor1, Matthew J Burton2, Danny Haddad3

  • 1Melbourne School of Population and Global Health, University of Melbourne, Carlton, VIC, Australia.

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|July 22, 2014
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El tracoma, una de las principales causas infecciosas de ceguera, es causado por Chlamydia trachomatis. La estrategia SAFE combate esta enfermedad a través de cirugía, antibióticos, limpieza facial y mejoras ambientales.

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Área de la Ciencia:

  • Oftalmología Oftalmología.
  • Enfermedades infecciosas Enfermedades infecciosas.
  • Salud Pública La salud pública.

Sus antecedentes:

  • El tracoma es la principal causa infecciosa de ceguera prevenible en todo el mundo.
  • Las infecciones por Chlamydia trachomatis en la infancia causan inflamación de la conjuntiva y cicatrización, lo que lleva a triquiasis ( pestañas invertidas).
  • La higiene inadecuada en entornos con escasos recursos facilita la transmisión de enfermedades.

Objetivo del estudio:

  • Para resumir la epidemiología, fisiopatología y control del tracoma.
  • Para resaltar la efectividad de la estrategia SAFE en los esfuerzos de eliminación del tracoma.

Principales métodos:

  • Revisión de los datos epidemiológicos y fisiopatológicos sobre el tracoma.
  • Descripción de los componentes integrados de la estrategia SAFE: cirugía, antibióticos, limpieza facial, mejora del medio ambiente.

Principales resultados:

  • La estrategia SAFE ha demostrado ser exitosa en la eliminación del tracoma en varios países.
  • Las iniciativas globales están trabajando activamente para la eliminación mundial del tracoma cegador.

Conclusiones:

  • Los programas de control integrado que utilizan la estrategia SAFE son efectivos en la lucha contra el tracoma.
  • Los esfuerzos globales continuados son esenciales para lograr el objetivo de eliminar el tracoma cegador para 2020.