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Parental Care00:55

Parental Care

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Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Fertilization01:38

Fertilization

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During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
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Relationship with Parents: Attachment01:28

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Parent-child interactions lay the foundation for how we understand relationships throughout life. These interactions are not uniform across families; instead, they are shaped by a range of environmental, emotional, and behavioral factors unique to each caregiver-child dynamic. Social psychologists study these early relationships to understand how patterns formed in infancy influence social functioning and interpersonal behavior in adulthood.Attachment Theory and Early Relational ModelsJohn...
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Development of the Oral Microbiota01:28

Development of the Oral Microbiota

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The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
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Imprinting01:22

Imprinting

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Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
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Video Experimental Relacionado

Updated: Apr 25, 2026

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

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La paternidad desde antes de la concepción.

Michelle Lane1, Rebecca L Robker1, Sarah A Robertson2

  • 1The Robinson Research Institute and School of Paediatrics and Reproductive Health, The University of Adelaide, Level 3, Medical School, South Adelaide, SA, 5005 Australia.

Science (New York, N.Y.)
|August 16, 2014
PubMed
Resumen
Este resumen es generado por máquina.

La edad de los padres y las exposiciones ambientales afectan el desarrollo del embrión a través de la información genómica y epigenómica. Estos factores, incluida la metilación del ADN y el ARN no codificante, influyen en la salud de por vida de un niño, comenzando antes de la concepción.

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Área de la Ciencia:

  • Biología Reproductiva Biología Reproductiva.
  • Biología del desarrollo Biología del desarrollo.
  • La epigenética es la epigenética.

Sus antecedentes:

  • La fertilización establece el plan genómico embrionario, influenciado por la edad y el entorno de los padres.
  • La historia y las experiencias de los padres afectan a la descendencia a través de la información epigenómica más allá de la secuencia de ADN.

Objetivo del estudio:

  • Explorar el papel de la información epigenómica parental en la programación del desarrollo embrionario y fetal.
  • Comprender cómo los efectos epigenéticos transgeneracionales influyen en los resultados de salud de por vida en los niños.

Principales métodos:

  • Revisión de estudios recientes sobre la influencia de los padres en la epigenética de la descendencia.
  • Análisis de las variaciones en la metilación de la citosina de los espermatozoides y los ovocitos, el patrón de la cromatina, los ARN no codificantes y las mitocondrias.

Principales resultados:

  • Los factores epigenómicos parentales, incluidos los ARN de metilación y no codificantes, se transmiten al embrión.
  • Estos efectos epigenéticos transgeneracionales interactúan con las condiciones de concepción para programar el desarrollo.

Conclusiones:

  • La información epigenómica de los padres influye significativamente en el desarrollo fetal y la salud de por vida.
  • La paternidad biológica comienza antes de la concepción, desafiando las nociones tradicionales del desarrollo prenatal.