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1Center for Microbial Oceanography: Research and Education, University of Hawaii, Manoa, Honolulu, HI 96822, USA; Department of Civil and Environmental Engineering and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Cell
|October 11, 2014
Resumen
Las comunidades microbianas de diversos entornos pueden colonizar con éxito el intestino de los mamíferos. Estas bacterias intestinales no nativas pueden establecerse y competir dentro de un huésped extraño, desafiando suposiciones anteriores.
Área de la Ciencia:
- Microbiología Microbiología.
- Ecología Ecología Ecología.
- El microbioma intestinal de los mamíferos
Sus antecedentes:
- La microbiota intestinal de los animales es típicamente específica del origen y la dieta del huésped.
- La capacidad de las bacterias no nativas para invadir y colonizar entornos intestinales extranjeros sigue siendo en gran medida desconocida.
Objetivo del estudio:
- Investigar la colonización y el éxito competitivo de bacterias de diversos orígenes no nativos dentro del entorno intestinal de los mamíferos.
Principales métodos:
- Introducción experimental de diversas comunidades microbianas en un modelo intestinal de mamíferos.
- Análisis de la composición de la comunidad microbiana y la dinámica competitiva.
Principales resultados:
- Las bacterias de una variedad de hábitats dispares demostraron una colonización exitosa en el intestino de los mamíferos.
- Las comunidades microbianas no nativas fueron capaces de competir efectivamente dentro del entorno intestinal establecido.
Conclusiones:
- El intestino de los mamíferos es más tolerante a la invasión por diversas comunidades microbianas de lo que se pensaba anteriormente.
- Los ecosistemas microbianos intestinales pueden ser más dinámicos y adaptables a las entradas microbianas externas.
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