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El ribosoma emerge de una caja negra
1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Cell
|November 24, 2014
Resumen
El descubrimiento de la estructura atómica y los mecanismos moleculares del ribosoma, conocidos desde hace mucho tiempo como un hecho básico, requirió una innovación persistente. Estos avances han transformado nuestra comprensión de la traducción celular.
Área de la Ciencia:
- Biología Molecular Biología Molecular
- Biología Estructural Biología estructural.
- La bioquímica es la bioquímica.
Sus antecedentes:
- El ribosoma, una máquina celular fundamental, ha sido estudiado durante décadas.
- Se estableció el conocimiento básico de la función del ribosoma, pero los mecanismos detallados seguían siendo elusivos.
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Ribosomes translate genetic information encoded by messenger RNA (mRNA) into proteins. Both prokaryotic and eukaryotic cells have ribosomes. Cells that synthesize large quantities of protein—such as secretory cells in the human pancreas—can contain millions of ribosomes.
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