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Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
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Updated: Apr 18, 2026

Micron-scale Resolution Optical Tomography of Entire Mouse Brains with Confocal Light Sheet Microscopy
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Micron-scale Resolution Optical Tomography of Entire Mouse Brains with Confocal Light Sheet Microscopy

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El microscopio. el microscopio. El cerebro súper resuelto.

Hans-Ulrich Dodt1

  • 1Vienna University of Technology, 1040 Vienna, Austria, and Medical University of Vienna, 1090 Vienna, Austria. dodt@tuwien.ac.at.

Science (New York, N.Y.)
|January 31, 2015
PubMed
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No abstract available in PubMed .

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