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Updated: Apr 15, 2026

A Semi-High-Throughput Adaptation of the NADH-Coupled ATPase Assay for Screening Small Molecule Inhibitors
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Descubrimiento de una sonda de molécula pequeña para la función de la V-ATPasa.

Leslie N Aldrich1,2, Szu-Yu Kuo2,3, Adam B Castoreno2

  • 1†Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States.

Journal of the American Chemical Society
|April 11, 2015
PubMed
Resumen

Los investigadores descubrieron una nueva molécula pequeña que altera la acidificación lisosomal. Este hallazgo avanza en la comprensión de la función del lisosoma y su papel en la homeostasis celular y la enfermedad.

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