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Updated: Apr 14, 2026

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains
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Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains

Published on: March 25, 2015

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Entrega intracelular eficiente de las proteínas nativas

Diego S D'Astolfo1, Romina J Pagliero2, Anita Pras3

  • 1KNAW-Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands.

Cell
|April 25, 2015
PubMed
Resumen

Desarrollamos la transducción inducida por osmocitosis y propanebetaína (iTOP), un nuevo método para la administración directa de proteínas a las células. Esta técnica proporciona eficientemente proteínas, incluido Cas9 para la edición de genes, en varios tipos de células.

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