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El Ribofilm como concepto de los orígenes de la vida
John A Baross1, William F Martin2
1School of Oceanography and Astrobiology Program, University of Washington, Seattle, WA 98195, USA.
Cell
|July 4, 2015
Resumen
Las arqueas más antiguas produjeron metano, apoyando la hipótesis de los respiraderos hidrotermales para el origen de la vida. Esto sugiere que el ARN actuó como una plataforma fundacional, no como un autorreplicador, en la vida temprana.
Área de la Ciencia:
- Astrobiología Astrobiología.
- La bioquímica es la bioquímica.
- Geología Geología Geología.
Sus antecedentes:
- Los datos filogenéticos sugieren que las primeras arqueas eran metanógenos.
- Las fuentes hidrotermales son una hipótesis líder para la abiogénesis.
- Se debate el papel del ARN en el origen de la vida.
Objetivo del estudio:
- Integrar los datos filogenéticos con las teorías de los respiraderos hidrotermales.
- Proponer un nuevo modelo para el papel del ARN en la vida temprana.
- Para apoyar la hipótesis de la abiogénesis dirigida termodinámicamente.
Principales métodos:
- Análisis filogenético de las arqueas.
- Modelado termodinámico de las primeras condiciones de la Tierra.
- Reconstrucción de las vías bioquímicas.
Principales resultados:
- Datos filogenéticos recientes indican que las primeras arqueas eran productoras de metano.
- Este hallazgo galvaniza la evidencia interdisciplinaria de que la vida se originó en fuentes hidrotermales.
- Se propone el concepto de una "ribofilm".
Conclusiones:
- La vida probablemente surgió a través de eventos termodinámicamente dirigidos en fuentes hidrotermales.
- El papel del ARN en el origen de la vida puede describirse mejor como una plataforma que cambia lentamente.
- Esto desafía la noción de ARN como un autorreplicador puramente espontáneo.
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