Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Chirality02:25

Chirality

32.5K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
32.5K
Prochirality02:05

Prochirality

5.4K
The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
5.4K
Chirality in Nature02:30

Chirality in Nature

18.0K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
18.0K
Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

16.5K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
16.5K
Stereoisomerism of Cyclic Compounds02:33

Stereoisomerism of Cyclic Compounds

11.9K
In this lesson, we delve into the role of ring conformation and its stability, which determines the spatial arrangement and, consequently, the molecular symmetry and stereoisomerism of cyclic compounds. 1,2-Dimethylcyclohexane is used as a case study to evaluate the possible number of stereoisomers. Here, given the multiple (n = 2) chiral centers, there are 2n = 4 possible configurations that lack a plane of symmetry, as the ring skeleton exists in a non-planar chair conformation. In addition,...
11.9K
Conjugated Proteins02:50

Conjugated Proteins

29.8K
Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
29.8K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Amplified chiroptic response in a multi-helical penta-perylene structure.

Chemical science·2026
Same author

Strong Coupling in Orthogonal Nanographenes.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Ion-Conductive Wires Form High-Performance All-Solid-State Polymer Electrolytes.

Journal of the American Chemical Society·2026
Same author

Twisted Graphene Nanoribbons for Breakthroughs in Energy Storage, Bioelectronics and Chiroptics.

Accounts of chemical research·2026
Same author

Transitory Topochemical Tailoring of a van der Waals Superconductor.

Journal of the American Chemical Society·2025
Same author

The "sweet spot" in length for contorted conjugated ladders in ultrafast-charging Li and Mg batteries.

Chemical science·2025
Same journal

A Ni-Mediated Cross-Coupling Approach to Deuterated <sup>18</sup>F- Fluoromethylated (Hetero)arenes.

Journal of the American Chemical Society·2026
Same journal

Efficient Light-Driven CO<sub>2</sub> Capture and Reversible Release Enabled by Metastable Photoacid-Decorated Metal-Organic Frameworks.

Journal of the American Chemical Society·2026
Same journal

In Situ Raman Spectroscopy Reveals the Dynamic Evolution and Ethanol Dependence of SEI Structure in Li-Mediated N<sub>2</sub> Reduction Reaction.

Journal of the American Chemical Society·2026
Same journal

Solvent Esterification and Stoichiometric Control in Ambient-Grown FAPbI<sub>3</sub> Single-Crystal Solar Cells.

Journal of the American Chemical Society·2026
Same journal

Unlocking Azulene Functionalization via Strain-Induced Azulyne Intermediates.

Journal of the American Chemical Society·2026
Same journal

An Oxazine-Locked Covalent Organic Framework by a Tandem Pinner/Schiff Base Reaction for Hydrogen Peroxide Photosynthesis.

Journal of the American Chemical Society·2026
Ver todos los artículos relacionados

Video Experimental Relacionado

Updated: Apr 6, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

12.2K

Corrales conjugados quirales

Melissa Ball1, Brandon Fowler1, Panpan Li2,1

  • 1†Department of Chemistry, Columbia University, New York, New York 10027, United States.

Journal of the American Chemical Society
|July 31, 2015
PubMed
Resumen
Este resumen es generado por máquina.

Los investigadores desarrollaron nuevos macrociclos conjugados con donantes de electrones alternos (bitiofeno) y aceptores (perileno diimida). Estas moléculas exhiben estereoisómeros únicos y un mecanismo de "salto intramolecular" para la interconversión.

Más Videos Relacionados

A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.8K
Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

8.4K

Videos de Experimentos Relacionados

Last Updated: Apr 6, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

12.2K
A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.8K
Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

8.4K

Área de la Ciencia:

  • Química orgánica
  • Química supramolecular
  • Ciencias de los materiales

Sus antecedentes:

  • Los macrociclos conjugados son cruciales en la química supramolecular.
  • El diseño de macrociclos con cavidades y propiedades electrónicas específicas sigue siendo un desafío.

Objetivo del estudio:

  • Introducir un nuevo motivo de diseño para macrociclos conjugados tensados.
  • Para crear macrociclos con unidades alternas de donantes y aceptadores de electrones.
  • Investigar la estereoquímica y la dinámica de estos nuevos macrociclos.

Principales métodos:

  • Síntesis de macrociclos con un patrón A-B-A-B utilizando el biotiofeno (donante) y el derivado de perileno diimida (aceptor).
  • Cromatografía líquida quiral de alto rendimiento (HPLC) para la separación de estereoisómeros.
  • Análisis espectroscópico y cálculos de la teoría funcional de la densidad (DFT).

Principales resultados:

  • Formación de macrociclos con una cavidad elíptica persistente revestida por átomos de azufre y las caras π del perilenodiimido.
  • Existencia de formas quirales y aquirales, con tres estereoisómeros separados con éxito.
  • Observación de un mecanismo de salto intramolecular para la interconversión de estereoisómeros.
  • Amplio espectro de absorción visible y transferencia de electrones inducida por la luz del bitioeno a la perileno diimida.

Conclusiones:

  • El nuevo motivo de diseño permite la construcción de macrociclos complejos, tensados y conjugados.
  • El mecanismo de salto intramolecular identificado ofrece información sobre la dinámica del macrociclo.
  • Estos macrociclos poseen interesantes propiedades fotofísicas debido a la transferencia intramolecular de electrones.