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Terapias farmacológicas y emergentes en el tratamiento de la angina crónica
Steen E Husted1, E Magnus Ohman2
1Department of Medicine, Hospital Unit West, Herning, Denmark; Department of Clinical Pharmacology, Institute of Biomedicine, Aarhus University, Aarhus, Denmark.
Lancet (London, England)
|September 4, 2015
Resumen
Los tratamientos médicos estándar y emergentes tienen como objetivo controlar la angina crónica, un síntoma de la enfermedad isquémica del corazón. Si bien existen terapias establecidas, la evidencia sólida para las opciones más nuevas contra la angina es limitada.
Área de la Ciencia:
- Cardiología
- Manejo de la enfermedad cardíaca isquémica
Sus antecedentes:
- La angina crónica es un síntoma frecuente de la enfermedad cardíaca isquémica.
- Los tratamientos médicos son cruciales para controlar la angina y mejorar la calidad de vida del paciente.
Objetivo del estudio:
- Revisar los tratamientos estándar, emergentes y experimentales para la angina crónica.
- Evaluar la base de pruebas actual para las terapias contra la angina.
Principales métodos:
- Revisión de la literatura sobre los tratamientos estándar de uso común (nitratos, bloqueadores beta y bloqueadores de los canales de calcio).
- Examen de las terapias emergentes y experimentales contra la angina.
- Análisis de la evidencia disponible sobre la eficacia del tratamiento para la angina y la isquemia.
Principales resultados:
- Los tratamientos establecidos como los nitratos, los bloqueadores beta y los bloqueadores de los canales de calcio son la atención estándar.
- Varios tratamientos emergentes contra la angina están disponibles a nivel mundial, pero con pruebas de apoyo limitadas.
- La evidencia con respecto a la eficacia de los tratamientos emergentes en la reducción de la angina y la isquemia es escasa.
Conclusiones:
- El tratamiento médico sigue siendo la piedra angular de la angina crónica.
- Se necesita más investigación para validar la eficacia de los tratamientos contra la angina emergentes.
- La brecha de evidencia para nuevas terapias requiere atención para mejorar los resultados de los pacientes.
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