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Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins
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Una estrategia efectiva para estabilizar los miméticos de bobina enrollados mínimos

Michael G Wuo1, Andrew B Mahon1, Paramjit S Arora1

  • 1Department of Chemistry, New York University , New York, New York 10003, United States.

Journal of the American Chemical Society
|September 5, 2015
PubMed
Resumen

Los investigadores desarrollaron un nuevo método para estabilizar las estructuras de proteínas en espiral en espiral utilizando enlaces covalentes. Esta estrategia mejora la modulación de la interacción proteína-proteína (IPP) para aplicaciones biomédicas.

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