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Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
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Determinación del destino celular por regulación de la traducción dependiente de la ubiquitina

Achim Werner1,2, Shintaro Iwasaki2, Colleen A McGourty2

  • 1Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA.

Nature
|September 25, 2015
PubMed
Resumen

La ubiquitina ligasa CUL3 ((KBTBD8) regula la especificación de las células de la cresta neural mediante la modificación de las proteínas involucradas en el síndrome de Treacher Collins. Este proceso tiene un impacto en la determinación del destino celular a través de la regulación de la traducción dependiente de la ubiquitina.

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