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La biogénesis de hapalindoles/ambiguinas está mediada por un reordenamiento de Cope, una cascada de formación de

Shasha Li, Andrew N Lowell, Fengan Yu

  • 1Department of Chemistry, Colorado State University , Fort Collins, Colorado 80523, United States.

Journal of the American Chemical Society
|December 3, 2015
PubMed
Resumen

Los investigadores han descubierto la vía biosintética para los hapalindolos, alcaloides complejos de indol. Las enzimas clave, FamD2 y FamC1, ensamblan la estructura del anillo central a partir de precursores específicos.

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