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Acute Coronary Syndrome IV: Interprofessional Care01:28

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Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
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Video Experimental Relacionado

Updated: Mar 29, 2026

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
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Intervenciones para la rosácea

Esther J van Zuuren1, Zbys Fedorowicz2

  • 1Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands.

JAMA
|December 10, 2015
PubMed
Resumen
Este resumen es generado por máquina.

Los tratamientos efectivos para la rosácea incluyen brimonidina tópica, ácido azelaico e ivermectina, además de doxiciclina y isotretinoína por vía oral. La mayoría de las terapias muestran tasas de eventos adversos similares a las del placebo, lo que indica buenos perfiles de seguridad para el tratamiento de la rosácea.

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Área de la Ciencia:

  • Dermatología
  • Farmacología
  • Terapéutica clínica

Sus antecedentes:

  • La rosácea es una enfermedad inflamatoria crónica de la piel que afecta la apariencia facial.
  • La identificación de opciones de tratamiento efectivas y seguras es crucial para el manejo del paciente.

Objetivo del estudio:

  • Evaluar la eficacia y seguridad de varias intervenciones para la rosácea.
  • Para comparar los resultados del tratamiento y los perfiles de eventos adversos.

Principales métodos:

  • Revisión sistemática y metanálisis de los ensayos clínicos.
  • Evaluación de la calidad de las pruebas para diferentes clases terapéuticas.

Principales resultados:

  • La evidencia de alta calidad apoya la brimonidina tópica, el ácido azelaico, la ivermectina, la doxiciclina oral y la isotretinoína para mejorar la rosácea.
  • Existen pruebas de menor calidad para el metronidazol tópico, la tetraciclina oral, la terapia con láser/luz y la ciclosporina tópica (rosacea ocular).
  • La mayoría de las intervenciones demostraron tasas de eventos adversos comparables a las del placebo.

Conclusiones:

  • Las terapias tópicas y orales ofrecen mejoras significativas para la rosácea.
  • Los tratamientos establecidos generalmente poseen perfiles de seguridad favorables.
  • Las investigaciones adicionales pueden reforzar la evidencia de otras modalidades, particularmente para la rosácea ocular.