Video Experimental Relacionado

Updated: Mar 27, 2026

Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study
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Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study

Published on: July 27, 2016

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El isoproterenol promueve el movimiento rápido de los receptores de ryanodina hacia los diados organizados por el

Ying Fu1, Seiji A Shaw1, Robert Naami1

  • 1From Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (Y.F., S.A.S., R.N., C.L.V., W.A.B., T.H.); Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (X.G.); and Departments of Medicine, Cedars-Sinai Medical Center and UCLA, Los Angeles, CA (T.H.).

Circulation
|January 7, 2016
PubMed
Resumen

El integrador puente 1 (BIN1) organiza las proteínas clave en las células del corazón para mejorar el manejo del calcio. La reducción de BIN1 en la insuficiencia cardíaca altera este proceso, lo que lleva a arritmias.

Palabras clave:
Proteína BIN1insuficiencia cardíacaMicrodominio de membranaMiocitos cardíacosreceptores adrenérgicos, betareceptor de ryanodine 2, ratón

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