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Updated: Mar 25, 2026

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Bases estructurales y moleculares para la neutralización del virus del Ébola mediante anticuerpos protectores humanos

John Misasi1, Morgan S A Gilman2, Masaru Kanekiyo3

  • 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Division of Infectious Diseases, Boston Children's Hospital, Boston, MA 02215, USA.

Science (New York, N.Y.)
|February 27, 2016
PubMed
Resumen

Dos anticuerpos monoclonales, mAb100 y mAb114, ofrecen protección contra la enfermedad del virus del Ébola al atacar la glicoproteína del virus. Su acción combinada impide la entrada del virus y la unión al receptor, allanando el camino para nuevas terapias.

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