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Asociarse con las grandes farmacéuticas: lo que los académicos necesitan saber
Stuart A Lipton1, Christer Nordstedt2
1Scintillon Institute, San Diego, CA 92121, USA; The Scripps Research Institute, La Jolla, CA 92037, USA; School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Cell
|April 23, 2016
Resumen
Los científicos académicos pueden mejorar las asociaciones con las compañías farmacéuticas mediante la comprensión de los parámetros clave del desarrollo de medicamentos. Las áreas clave incluyen estudios de farmacodinámica, farmacocinética y toxicidad, junto con la eficacia preclínica, para el desarrollo de nuevos tratamientos.
Área de la Ciencia:
- Desarrollo de fármacos
- Ciencias farmacéuticas
- Colaboración entre la academia y la industria
Sus antecedentes:
- Los científicos académicos a menudo buscan asociaciones farmacéuticas para el desarrollo de nuevos tratamientos.
- La comprensión de los parámetros del desarrollo de fármacos es crucial para una colaboración exitosa de la industria.
Objetivo del estudio:
- Para aclarar los parámetros críticos del desarrollo de fármacos para científicos académicos.
- Destacar la importancia de los estudios de farmacodinámica, farmacocinética y toxicidad para las asociaciones industriales.
Principales métodos:
- Revisión de las etapas clave del desarrollo de fármacos.
- Discusión de los parámetros preclínicos y clínicos esenciales.
- Análisis de los factores críticos para la participación de las empresas farmacéuticas.
Principales resultados:
- Los estudios farmacodinámicos, farmacocinéticos y de toxicidad son los pilares principales del desarrollo de fármacos.
- La eficacia preclínica también es vital para el avance terapéutico.
- Estos parámetros informan colectivamente las asociaciones exitosas de Big Pharma.
Conclusiones:
- El conocimiento de los parámetros de desarrollo de fármacos facilita la colaboración entre la academia y la industria.
- Centrarse en la farmacodinámica, la farmacocinética, la toxicidad y la eficacia es esencial para la creación de nuevos medicamentos.
- Las asociaciones exitosas aceleran la producción de nuevos fármacos.
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