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Updated: Mar 19, 2026

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
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Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth

Published on: January 7, 2022

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Actividad de formación de poros y autoinhibición estructural de la familia de las gasderminas

Jingjin Ding, Kun Wang, Wang Liu

    Nature
    |June 10, 2016
    PubMed
    Resumen

    Los dominios de gasdermina-N interrumpen las membranas celulares, formando poros cruciales para la piroptosis (muerte celular programada). Este descubrimiento aclara el mecanismo de las proteínas de gasdermina en la inmunidad y la enfermedad.

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