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RNA Splicing01:32

RNA Splicing

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Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
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RNA Splicing01:32

RNA Splicing

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Pre-mRNA Processing: RNA Splicing01:36

Pre-mRNA Processing: RNA Splicing

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Chromatin Structure and RNA Splicing02:41

Chromatin Structure and RNA Splicing

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Alternative RNA Splicing02:18

Alternative RNA Splicing

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Alternative RNA Splicing02:18

Alternative RNA Splicing

25.9K
Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
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Productive mRNA chromatin escape is promoted by PRMT5 activity.

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Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation.

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Video Experimental Relacionado

Updated: Mar 16, 2026

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency
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A Reporter Based Cellular Assay for Monitoring Splicing Efficiency

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Biología estructural: Esplice catalítico capturado

Brian Kosmyna1, Charles C Query1

  • 1Department of Cell Biology, Albert Einstein College of Medicine, New York, New York 10461-1975, USA.

Nature
|August 12, 2016
PubMed
Resumen

No abstract available in PubMed .

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