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Updated: Mar 16, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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Análogo del ácido biliar intercepta la fibrosis hepática

C Daniel De Magalhaes Filho1, Michael Downes1, Ron Evans1

  • 1Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

Cell
|August 13, 2016
PubMed
Resumen

Ocaliva, un análogo sintético del ácido biliar, trata eficazmente la colangitis biliar primaria en pacientes que no responden al ácido ursodeoxicólico (UDCA). Este agonista de la FXR ofrece una alternativa para el tratamiento de la enfermedad hepática autoinmune.

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