Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

17.8K
The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
17.8K
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

4.0K
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
4.0K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

11.2K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
11.2K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

85.7K
Overview
85.7K
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

17.0K
T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
17.0K
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

1.8K
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
1.8K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Author Correction: A route for cerebrospinal fluid flow through leptomeningeal arterial-venous overlaps enables macromolecule and fluid shunting.

Nature neuroscience·2026
Same author

Exploring Lymphovenous Anastomosis for Alzheimer's Disease: Addressing Brain Lymphatic Dysfunction, Feasibility, and Outcome Metrics.

Plastic and reconstructive surgery·2026
Same author

Astrocytic cholesterol jams brain clearance in AD.

Nature neuroscience·2026
Same author

Skull bone marrow immunity in brain health and disease: mechanisms and models.

Journal of immunology (Baltimore, Md. : 1950)·2026
Same author

Brain-engrafted monocyte-derived macrophages from blood and skull-bone marrow exhibit distinct properties.

Neuron·2026
Same author

Engineering chimeric antigen receptor CD4 T cells for Alzheimer's disease.

Proceedings of the National Academy of Sciences of the United States of America·2026

Video Experimental Relacionado

Updated: Mar 16, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
09:38

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

12.9K

Interacciones multifacéticas entre la inmunidad adaptativa y el sistema nervioso central

Jonathan Kipnis1

  • 1Center for Brain Immunology and Glia (BIG), Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.

Science (New York, N.Y.)
|August 20, 2016
PubMed
Resumen

Esta revisión explora la intrincada relación entre el sistema nervioso central (SNC) y el sistema inmunológico. Destaca las preguntas clave en neuroinmunología con respecto al papel de las células inmunes en la salud, la enfermedad y la lesión del SNC.

Más Videos Relacionados

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
08:47

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

Published on: May 8, 2016

25.0K
Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier
09:00

Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier

Published on: April 5, 2017

21.0K

Videos de Experimentos Relacionados

Last Updated: Mar 16, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
09:38

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

12.9K
Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
08:47

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

Published on: May 8, 2016

25.0K
Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier
09:00

Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier

Published on: April 5, 2017

21.0K

Área de la Ciencia:

  • Neuroinmunología
  • Investigación del sistema nervioso central (SNC)
  • Inmunidad adaptativa

Sus antecedentes:

  • El sistema nervioso central y el sistema inmunológico presentan interacciones complejas.
  • Comprender estas interacciones es crucial tanto para las afecciones homeostáticas como para las enfermedades neurológicas.
  • Existen brechas de conocimiento clave con respecto al comportamiento de las células inmunes dentro del SNC.

Objetivo del estudio:

  • Para resumir la comprensión actual de la inmunidad adaptativa y las interacciones del SNC.
  • Identificar y discutir preguntas críticas sin respuesta en neuroinmunología.
  • Proyectar las direcciones futuras de la investigación en el campo durante la próxima década.

Principales métodos:

  • Revisión de la literatura científica actual sobre neuroinmunología.
  • Análisis de la investigación existente sobre la diversidad y la especificidad del repertorio de células T en las meninges.
  • Examen de las rutas de tráfico de células inmunes hacia y dentro del SNC.

Principales resultados:

  • La revisión consolida los conocimientos actuales sobre el papel de las células inmunes en la homeostasis y la patología del SNC.
  • Identifica desafíos específicos, incluida la comprensión de la diversidad de células T meníngeas y los efectos de las células inmunes en la función del SNC.
  • Se destaca la interdependencia evolutiva de los sistemas nervioso e inmunológico.

Conclusiones:

  • Quedan preguntas importantes con respecto a la especificidad de las células inmunes, el tráfico y el impacto funcional dentro del SNC.
  • Se necesita más investigación para dilucidar el papel de las células inmunes en la lesión y enfermedad del SNC.
  • El campo de la neuroinmunología está preparado para avances significativos en la comprensión de la interacción entre el SNC y el sistema inmunológico.