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Examen de detección de la infección por tuberculosis latente en adultos: Declaración de recomendación del grupo de
, Kirsten Bibbins-Domingo1, David C Grossman2
1University of California, San Francisco.
JAMA
|September 7, 2016
Resumen
Se recomienda la detección de la infección por tuberculosis latente (LTBI) para las personas con mayor riesgo. El tratamiento de LTBI ofrece beneficios moderados en la prevención de la enfermedad de tuberculosis activa con daños mínimos.
Área de la Ciencia:
- Salud pública
- La medicina preventiva
- Epidemiología de las enfermedades infecciosas
Sus antecedentes:
- La tuberculosis (TB) es una enfermedad importante y prevenible en los EE.UU.
- La identificación y el tratamiento de la infección de tuberculosis latente (LTBI) es clave para reducir la transmisión, la enfermedad y la muerte por tuberculosis.
- La prevención de la progresión de la TB de larga duración a la enfermedad activa es un objetivo primordial de salud pública.
Objetivo del estudio:
- Proporcionar una recomendación actualizada de la Fuerza de Tarea de Servicios Preventivos de los Estados Unidos (USPSTF, por sus siglas en inglés) sobre el cribado de la LTCI.
- Informar a las prácticas de atención primaria sobre las directrices actuales para el cribado de ITL.
Principales métodos:
- Revisión sistemática de la evidencia sobre el cribado de ITA en adultos asintomáticos en la atención primaria.
- Incluir pruebas de los registros de base de datos más antiguos disponibles.
Principales resultados:
- Se dispone de pruebas de detección precisas para el LTBI.
- El tratamiento para la LTI proporciona un beneficio moderado en la prevención de la progresión activa de la enfermedad.
- Los daños asociados con el cribado y el tratamiento de la LTI se consideran pequeños.
Conclusiones:
- El USPSTF recomienda el cribado de LTBI en poblaciones identificadas como de mayor riesgo.
- Esta recomendación se designa como recomendación "B", lo que indica una gran certeza de un beneficio neto moderado.
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