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Updated: Mar 14, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Fluoración C-H catalizada por hierro y dirigida por fluoroamida

Brian J Groendyke1, Deyaa I AbuSalim1, Silas P Cook1

  • 1Department of Chemistry, Indiana University , 800 East Kirkwood Avenue, Bloomington, Indiana 47405-7102, United States.

Journal of the American Chemical Society
|September 28, 2016
PubMed
Resumen

Este estudio introduce un nuevo método catalizado por el hierro para la fluoración leve de C-H utilizando N-fluoro-2-metilbenzamidas. Este enfoque convierte eficientemente varios enlaces C-H en fluoruros, ofreciendo una herramienta valiosa para la síntesis orgánica.

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