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Catalizador de iridio con ligando de borilo N,B-bidentado para la borilación eficiente dirigida por grupos

Guanghui Wang¹, Li Liu¹, Hong Wang¹

¹Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, 710054, China.

Journal of the American Chemical Society

|December 20, 2016

Resumen

Los investigadores desarrollaron nuevos compuestos de sililborano para crear complejos de iridio (III). Estos precursores permiten una eficiente ortoborilación catalítica de arenas, ofreciendo un método práctico para sintetizar compuestos orgánicos valiosos.

Área de la Ciencia:

Química organometálica
Catálisis
Química sintética

Sus antecedentes:

Los complejos de metales de transición son catalizadores cruciales en la síntesis orgánica.
Es esencial desarrollar métodos eficientes para la síntesis de ligandos y la formación de complejos metálicos.
Los sililboranos ofrecen una reactividad única para la introducción de ligandos que contienen boro.

Objetivo del estudio:

Para diseñar y sintetizar nuevos precursores de sililborano.
Para utilizar estos precursores para la formación de complejos de iridio.
Desarrollar una reacción de orto-borilación catalítica de arenas.

Principales métodos:

Síntesis de los precursores del sililborano
Formación de complejos de iridio (III) mediante adición oxidativa de Si-B.
Generación de catalizadores in situ utilizando el preligando de sililborano 3c y [IrCl ((COD)) ]2 para la berilación.

Principales resultados:

Se diseñaron y prepararon con éxito precursores convenientes de sililborano.
Los complejos de iridio (III) se formaron fácilmente a través de la adición oxidativa de Si-B.
Se logró una eficiente orto-borilación catalítica de varias arenas.

Conclusiones:

Los precursores de sililborano desarrollados son eficaces para la introducción del ligando borilo N,B-bidentato.
El sistema catalítico proporciona una vía práctica y eficiente para la ortoborilación del areno.
Este trabajo amplía la utilidad de los sililboranos en química organometálica y catálisis.

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