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Updated: Mar 8, 2026

Author Spotlight: Functionalizing Metal-Organic Frameworks: Advancements, Challenges, and the Power of Post-Synthetic Ligand Exchange
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Funcionalización heteroatómica de liberación de tensión: desarrollo, alcance y estereospecificidad

Justin M Lopchuk1, Kasper Fjelbye1, Yu Kawamata1

  • 1Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|February 1, 2017
PubMed
Resumen

Los químicos farmacéuticos ahora pueden instalar fácilmente anillos tensados como el biciclo[1.1.1]pentano en el descubrimiento de fármacos utilizando una nueva estrategia de liberación de tensión. Este método permite la funcionalización de "cualquier etapa", simplificando la síntesis de moléculas complejas.

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