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Updated: Mar 8, 2026

Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo
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Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

Published on: March 31, 2016

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Homer1a impulsa la reducción homeostática de las sinapsis excitatorias durante el sueño

Graham H Diering1, Raja S Nirujogi2, Richard H Roth1

  • 1Solomon Snyder Department of Neuroscience, Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA.

Science (New York, N.Y.)
|February 4, 2017
PubMed
Resumen

Durante el sueño, las sinapsis se debilitan a través de la eliminación de receptores, un proceso impulsado por la señalización de Homer1a y mGluR1/5. Esta remodelación sináptica ayuda a consolidar los recuerdos.

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