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Updated: Mar 7, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

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2-aminopirimidinas sustituidas selectivas para la activación del receptor α7-nicotínico de acetilcolina y la

Katarzyna Kaczanowska1, Gisela Andrea Camacho Hernandez1,2, Larissa Bendiks1

  • 1Department of Pharmacology, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego , La Jolla, California 92093-0650, United States.

Journal of the American Chemical Society
|February 22, 2017
PubMed
Resumen

Los investigadores desarrollaron nuevas 2-aminopirimidinas que activan el receptor alfa7 de acetilcolina nicotínica (α7-nAChR). Estos compuestos muestran una unión específica, ofreciendo potencial para nuevas estrategias terapéuticas dirigidas a los receptores nicotínicos de acetilcolina.

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