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Vaccinations01:51

Vaccinations

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Overview
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Leaky Scanning02:28

Leaky Scanning

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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Viral Recombination00:57

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Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
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Pneumonia I: Introduction01:30

Pneumonia I: Introduction

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
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Updated: Mar 6, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

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La gripe

Catharine Paules1, Kanta Subbarao1

  • 1Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Lancet (London, England)
|March 18, 2017
PubMed
Resumen

La gripe, una enfermedad respiratoria viral, presenta diversos síntomas y puede causar epidemias estacionales o pandemias. Las nuevas estrategias de prevención y tratamiento son cruciales para gestionar las amenazas de la gripe.

Área de la Ciencia:

  • Virología
  • Epidemiología
  • Salud pública

Sus antecedentes:

  • La gripe es una enfermedad respiratoria aguda causada por los virus de la influenza A, B y C.
  • Ocurre en brotes locales o epidemias estacionales, con una presentación clínica muy variable.
  • Los virus de la influenza A representan una amenaza pandémica cuando surgen nuevas cepas de los animales huéspedes.

Objetivo del estudio:

  • Para discutir la presentación clínica, la transmisión, el diagnóstico, el manejo y la prevención de la gripe estacional.
  • Para revisar la interfaz animal-humano de la gripe.
  • Para resaltar las amenazas pandémicas actuales y la necesidad de nuevos enfoques.

Principales métodos:

  • Revisión de la literatura y síntesis de los conocimientos actuales sobre la gripe.

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  • Discusión de los aspectos clínicos, incluida la presentación y el diagnóstico.
  • Análisis de la dinámica de transmisión y estrategias de prevención.
  • Principales resultados:

    • Las epidemias de gripe estacional y las infecciones esporádicas son comunes.
    • Las nuevas cepas de influenza A pueden provocar pandemias mundiales.
    • Comprender la interfaz animal-humano es clave para la preparación para una pandemia.

    Conclusiones:

    • La gestión eficaz de la gripe estacional y las amenazas pandémicas requiere estrategias de prevención y tratamiento actualizadas.
    • Es esencial seguir investigando la virología y la transmisión de la gripe.
    • Abordar la interfaz animal-humano es crítico para mitigar futuras pandemias.