Un sitio de unión del factor nuclear 1 media la activación transcripcional de un promotor de colágeno tipo I mediante

P Rossi1, G Karsenty, A B Roberts

  • 1Laboratory of Molecular Biology, National Cancer Institute, Bethesda, Maryland 20892.

Cell
|February 12, 1988
PubMed
Resumen

El factor de crecimiento transformador-beta (TGF-beta) activa la transcripción del gen del colágeno. Este proceso requiere un sitio específico de unión al factor nuclear 1 (NF1), lo que demuestra su papel crucial en el TGF-beta.

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