Video Experimental Relacionado
Updated: Jun 10, 2026
10:38
Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
Published on: September 27, 2012
Mutación del gen del reloj circadiano humano CRY1 en el trastorno de la fase de sueño retrasado familiar
Alina Patke1, Patricia J Murphy2, Onur Emre Onat3
1Laboratory of Genetics, The Rockefeller University, New York, NY 10065, USA.
Cell
|April 8, 2017
Resumen
Una variación genética en el gen CRY1 causa trastorno de la fase tardía del sueño (DSPD), una forma de insomnio. Esto lleva a horas de sueño más tardías y altera los ritmos circadianos en las personas afectadas.
Área de la Ciencia:
- Cronología
- La genética
- Medicina del sueño
Sus antecedentes:
- Los ritmos circadianos humanos están regulados por un reloj biológico intrínseco, que asegura ciclos de aproximadamente 24 horas en la fisiología y el comportamiento.
- El trastorno de la fase tardía del sueño (DSPD) es un trastorno prevalente del sueño caracterizado por una desalineación del horario del sueño con las normas sociales.
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