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Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
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Cadros orgánicos covalentes quirales con alta estabilidad química para catálisis asimétrica heterogénea
Xing Han1, Qingchun Xia1, Jinjing Huang1
1School of Chemistry and Chemical Engineering and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University , Shanghai 200240, China.
Journal of the American Chemical Society
|June 10, 2017
Resumen
Se sintetizaron estructuras orgánicas covalentes quirales (CCOF) con mayor estabilidad y actividad catalítica. Estos CCOF que contienen metales demuestran una catálisis heterogénea eficiente para varias reacciones asimétricas, ofreciendo reciclabilidad y alta enantioselectividad.
Área de la Ciencia:
- Ciencias de los materiales
- Química orgánica
- Catálisis
Sus antecedentes:
- Los marcos orgánicos covalentes quirales (CCOF) son cruciales para la ciencia fundamental y aplicada.
- El logro de la quiralidad, la estabilidad y la funcionalidad en los FOC sigue siendo un desafío importante.
Objetivo del estudio:
- Informar sobre la síntesis dirigida a los metales de los nuevos COF quirales (CCOF).
- Investigar la estabilidad y las aplicaciones catalíticas de estos CCOF.
Principales métodos:
- Las condensaciones de imina de enantiopuro 1,2-diaminociclohexano con trisalicilaldehídos C3-simétricos.
- Difracción de rayos X en polvo, estudios de modelado y análisis de la distribución del tamaño de los poros.
- Intercambio de metales post-sintéticos para la incorporación de metales multivariados.
Principales resultados:
- Se sintetizaron dos CCOF basados en Zn ((salen) con una red hexagonal 2D y apilamiento de AA.
- Los CCOF con grupos tert-butilo mostraron una estabilidad química significativamente mejorada en condiciones ácidas y básicas.
- Los CCOF intercambiados mantuvieron la cristalinidad y la porosidad, sirviendo como catalizadores heterogéneos eficientes.
Conclusiones:
- Los CCOF sintetizados ofrecen una mayor estabilidad y funcionalidad ajustable a través del intercambio de metales.
- Estos CCOF son catalizadores heterogéneos eficaces y reciclables para diversas reacciones asimétricas, alcanzando hasta un 97% de exceso enantiomérico (ee).
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