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Electron Transport Chain: Complex III and IV01:43

Electron Transport Chain: Complex III and IV

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During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
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Electron Transport Chain: Complex I and II01:46

Electron Transport Chain: Complex I and II

19.3K
The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
19.3K
Colors and Magnetism03:02

Colors and Magnetism

14.3K
Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
14.3K
Metal-Ligand Bonds02:51

Metal-Ligand Bonds

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The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
24.8K
Formation of Complex Ions03:45

Formation of Complex Ions

26.5K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
26.5K
Complexometric Titration: Overview00:39

Complexometric Titration: Overview

12.5K
Complexometric titration involves the formation of a complex by reacting a metal ion with one or more ligands. A visual indicator often detects the end point of a complexometric titration. It is added to the metal solution before the titration, forming a stable metal–indicator complex and imparting color to the solution. As the titration approaches the equivalence point, the excess of the added ligand displaces the indicator from the metal–indicator complex, releasing the free...
12.5K

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Updated: Feb 28, 2026

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

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Un complejo mononuclear de hierro no hemo V-Imido

Seungwoo Hong1,2, Kyle D Sutherlin3, Anil Kumar Vardhaman1

  • 1Department of Chemistry and Nano Science, Ewha Womans University , Seoul 03760, Korea.

Journal of the American Chemical Society
|June 20, 2017
PubMed
Resumen

Los investigadores sintetizaron el primer complejo de hierro no hemo mononuclear utilizando un ligando tetramido macrocíclico (TAML). Este nuevo complejo de hierro exhibe propiedades espectroscópicas únicas y reactividad en la funcionalización C-H y las reacciones de transferencia de nitreno.

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Área de la Ciencia:

  • Química inorgánica
  • Química organometálica
  • Química bioorgánica

Sus antecedentes:

  • Se conocen complejos de hierro no hemo mononucleares.
  • La síntesis y caracterización de nuevos complejos de hierro de alta valencia son cruciales para comprender su reactividad.

Objetivo del estudio:

  • Informar el primer ejemplo de un complejo de hierro no hemo mononuclear V-imido.
  • Para caracterizar el complejo espectroscópicamente.
  • Investigar su reactividad en las reacciones de funcionalización de C-H y transferencia de nitreno.

Principales métodos:

  • Síntesis del complejo de hierro (V) imido que contiene un ligando tetramido macrocíclico (TAML).
  • Caracterización espectroscópica que incluye la determinación del estado de oxidación, la longitud del enlace Fe-N y la vibración Fe-N.
  • Estudios de reactividad centrados en la funcionalización de enlaces C-H y la transferencia de nitreno.

Principales resultados:

  • Se sintetizó con éxito el primer complejo de hierro no hemo mononuclear, [TAML) Fe (NTs) -1).
  • Los datos espectroscópicos confirmaron un estado de oxidación S = 1/2 Fe ((V), una longitud de enlace Fe-N de 1,65 ((4) Å, y una vibración Fe-N a 817 cm−1.
  • El complejo 1 demostró reactividad en la funcionalización de enlaces C-H y en las reacciones de transferencia de nitreno.

Conclusiones:

  • Este estudio presenta un nuevo complejo de hierro-V con características estructurales y espectroscópicas únicas.
  • Los hallazgos amplían el alcance de los complejos de hierro no hemo mononucleares conocidos.
  • La reactividad demostrada pone de relieve el potencial de este complejo en aplicaciones catalíticas.