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¿Un brote de herpes zóster?
Lancet (London, England)
|November 16, 1985
Resumen
Un brote de oficina mostró una mayor incidencia de herpes zóster de lo esperado. Esto sugiere que la reexposición al virus de la varicela-zoster puede desencadenar herpes zóster, especialmente después de una enfermedad anterior.
Área de la Ciencia:
- Epidemiología La epidemiología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Virología Virología.
Sus antecedentes:
- El herpes zóster es causado por la reactivación del virus varicela-zoster (VZV).
- Aunque por lo general es esporádica, la comprensión de la dinámica de los brotes y los desencadenantes es crucial para la salud pública.
- La enfermedad previa es un factor de riesgo conocido para la reactivación del VZV.
Objetivo del estudio:
- Para investigar un grupo inusual de casos de herpes zóster dentro de un departamento específico de un complejo de oficinas.
- Para determinar los posibles factores de riesgo y desencadenantes de herpes zóster durante este brote.
- Explorar el papel de la reexposición al VZV en el desarrollo de la culebrilla.
Principales métodos:
- Epidemiología descriptiva de los casos de herpes zóster dentro del complejo de oficinas.
- Pruebas serológicas de anticuerpos IgM específicos del virus varicela-zoster en casos y controles.
- Estudio caso-control para identificar factores de riesgo, incluida una enfermedad reciente anterior.
Principales resultados:
- La incidencia de herpes zóster fue significativamente mayor en el departamento de índice en comparación con la fuerza laboral general.
- Se detectaron anticuerpos IgM específicos del VZV en los casos de brote, pero no en los controles.
- Se observó la agrupación de casos en el tiempo y por área de trabajo.
- La enfermedad reciente anterior fue identificada como un factor de riesgo para el herpes zóster en los casos de brotes.
Conclusiones:
- El brote de culebrilla observado sugiere que la reexposición al virus varicela-zoster puede provocar culebrilla.
- La enfermedad previa puede aumentar la susceptibilidad a la reactivación del VZV y el desarrollo de herpes zóster.
- Los entornos laborales requieren la consideración de potenciales dinámicas de transmisión de VZV durante los brotes.
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