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La morfina sistémica mejora la propagación de la analgesia sensorial durante la infusión epidural postoperatoria de
Lancet (London, England)
|November 23, 1985
Resumen
La morfina sistémica mejoró la analgesia epidural con bupivacaína en pacientes con cirugía abdominal. Esta combinación mejoró el alivio del dolor postoperatorio al aumentar el bloqueo sensorial y reducir las puntuaciones de dolor.
Área de la Ciencia:
- Anestesiología Anestesiología.
- Manejo del dolor Manejo del dolor.
- Farmacología Farmacología.
Sus antecedentes:
- La analgesia epidural es crucial para el manejo del dolor postoperatorio.
- La bupivacaína se usa comúnmente para la anestesia epidural.
- La regresión de la analgesia epidural puede conducir a un dolor agudo.
Objetivo del estudio:
- Investigar el efecto sinérgico de la morfina sistémica en la analgesia epidural con bupivacaína.
- Para evaluar el impacto en los puntajes de bloqueo sensorial y dolor.
- Para determinar el potencial para mejorar el alivio del dolor postoperatorio.
Principales métodos:
- Ocho pacientes sometidos a cirugía abdominal recibieron una infusión epidural continua de bupivacaína.
- Los niveles de analgesia sensorial y las puntuaciones de dolor se monitorearon cada hora.
- Se administró morfina intravenosa cuando la analgesia regresó en 5 segmentos.
Principales resultados:
- La bupivacaína epidural sola mostró una regresión en la analgesia sensorial y un aumento en las puntuaciones de dolor.
- La administración sistémica de morfina condujo a un aumento significativo del cefalado en la analgesia sensorial.
- Las puntuaciones de dolor disminuyeron a casi cero después de la administración de morfina, con infusión sostenida de bupivacaína.
Conclusiones:
- La morfina sistémica exhibe un efecto sinérgico con la bupivacaína epidural.
- Esta terapia de combinación puede restaurar y mejorar la analgesia epidural.
- Los hallazgos sugieren una estrategia valiosa para mejorar el manejo del dolor postoperatorio.
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