Video Experimental Relacionado

Updated: Feb 25, 2026

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

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Cómo los ligandos iluminan la farmacología molecular de la GPCR

Daniel Wacker1, Raymond C Stevens2, Bryan L Roth1

  • 1Department of Pharmacology and Division of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27514, USA.

Cell
|July 29, 2017
PubMed
Resumen

Los receptores acoplados a proteínas G (GPCR) son objetivos clave de los fármacos. Una nueva investigación revela cómo diversos ligandos modulan los GPCR, acelerando el descubrimiento de nuevos medicamentos para diversas enfermedades.

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